![]() The authors conclude that metal dermatitis is a frequent and potentially debilitating disease which can be prevented. A memory effect was suggested as the underlying cause for repeated flareups, probably resulting from attachment of metal ions to specific proteins and subsequent antigen formation. ![]() Cure rates for nickel, chromium, and cobalt dermatitis were indicated to be about 25 percent. Mercury poisoning is a debilitating disease that can be fatal.The disease is caused by mercury that reacts with essential enzymes leading to irreversible inactivity of these enzymes.If the amount of mercury in a polluted lake is 0. The clinical course of metal dermatitis was discussed, including flareups with exposure subsequent to the sensitizing event, secondary spread of the dermatitis, and increased severity of allergy with repeated exposure. ![]() The prevalence of nickel and cobalt sensitization was highest in females. Chromate (13907454) dermatitis was observed to be caused primarily by occupational exposures to wet cement and was most prevalent in males. Causes of nickel dermatitis included exposure to nickel plated articles such as jewelry and clothing accessories and sensitization to the nickel ion through corrosion of the metal by sweat. The clinical pattern of nickel dermatitis was discussed as typical of metal contact dermatitis. Mercury poisoning is a debilitating disease that is often fatal. The remaining metals, such as antimony (7440360), arsenic (7440382), beryllium (7440417), tin (7440315), and uranium (7440611) were considered in terms of occupational exposure. Most metals considered were not likely to affect the general population, except for chromium (7440473), nickel (7440020), cobalt (7440484), and mercury (7439976). The toxicity of mercury (Guzzi La Porta, 2008) was highlighted by Minamata disease, first discovered in Minamata city in Kumamoto prefecture, Japan, in 1956. Twenty one metals and metalloids were considered for their adverse cutaneous effects most caused contact dermatitis, irritant dermatitis, granulomas, photosensitivity, urticaria, or discoloration. Chronic exposure to metals and their compounds resulting in metal contact dermatitis was discussed.
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